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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLD1 All Species: 42.42
Human Site: Y818 Identified Species: 62.22
UniProt: Q13393 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13393 NP_001123553.1 1074 124184 Y818 E N Q K Y R V Y V V I P L L P
Chimpanzee Pan troglodytes XP_526380 1125 128795 Y869 E N Q K Y R V Y V V L P L L P
Rhesus Macaque Macaca mulatta XP_001085464 1074 124020 Y818 E N Q K Y R V Y V V I P L L P
Dog Lupus familis XP_545291 1075 123911 Y819 E G Q R Y R V Y V V I P L L P
Cat Felis silvestris
Mouse Mus musculus Q9Z280 1074 123950 Y818 E G Q R Y R V Y I V I P L L P
Rat Rattus norvegicus P70496 1074 123795 Y818 E G Q R Y R V Y I V I P L L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513744 295 33781 H83 G R W D D N E H R L T D V G S
Chicken Gallus gallus XP_422793 1072 123414 Y817 E N K R Y R V Y V V I P L L P
Frog Xenopus laevis NP_001129642 1039 119219 Y783 E N K R Y R V Y V I T P L L P
Zebra Danio Brachydanio rerio NP_001153567 1022 117847 Y766 E N K K F R V Y V V T P L L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137610 1364 155352 Y1103 E R K P F R V Y V I M P L L P
Honey Bee Apis mellifera XP_001121004 1135 129725 F878 E G A V F R V F V V M P L L P
Nematode Worm Caenorhab. elegans NP_494939 1427 163517 Y1164 E K D N Y R V Y I M I P L L P
Sea Urchin Strong. purpuratus XP_784455 790 90080 Q578 A I L Q R L Y Q E D I T S P E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9W8 1046 118792 V772 E N K C F R V V I V I P L L P
Baker's Yeast Sacchar. cerevisiae P36126 1683 195185 F1017 E K K P W K A F I L I P L M P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.7 97.8 91 N.A. 91 90.6 N.A. 22 79.4 75.6 66.6 N.A. 34.8 40.3 35.9 35.1
Protein Similarity: 100 92 99 95.1 N.A. 95.6 95.6 N.A. 24.8 88.8 86.3 78.3 N.A. 50.9 57.7 51 49.5
P-Site Identity: 100 93.3 100 86.6 N.A. 80 80 N.A. 0 86.6 73.3 80 N.A. 60 60 66.6 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 20 100 93.3 93.3 N.A. 86.6 80 80 13.3
Percent
Protein Identity: N.A. N.A. N.A. 30.6 21 N.A.
Protein Similarity: N.A. N.A. N.A. 50.6 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. 66.6 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 0 0 7 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 7 7 0 0 0 0 7 0 7 0 0 0 % D
% Glu: 88 0 0 0 0 0 7 0 7 0 0 0 0 0 7 % E
% Phe: 0 0 0 0 25 0 0 13 0 0 0 0 0 0 0 % F
% Gly: 7 25 0 0 0 0 0 0 0 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 32 13 63 0 0 0 0 % I
% Lys: 0 13 38 25 0 7 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 7 0 0 7 0 0 0 13 7 0 88 82 0 % L
% Met: 0 0 0 0 0 0 0 0 0 7 13 0 0 7 0 % M
% Asn: 0 44 0 7 0 7 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 13 0 0 0 0 0 0 0 88 0 7 88 % P
% Gln: 0 0 38 7 0 0 0 7 0 0 0 0 0 0 0 % Q
% Arg: 0 13 0 32 7 82 0 0 7 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 19 7 0 0 0 % T
% Val: 0 0 0 7 0 0 82 7 57 63 0 0 7 0 0 % V
% Trp: 0 0 7 0 7 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 57 0 7 69 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _